Multiscale integration of neural, social, and network theory to understand and predict transitions from illness to wellness: a proof of concept with mindfulness, hypnosis and alcohol use disorders

Grant Number: 
Army Research Office
Date Range: 
02 Jul 2018 to 01 Jul 2021
Principal Investigators: 

Our overarching goal is to develop a causal multiscale model of intra-individual (i.e. neural, cognitive, physiological) and extra-individual (i.e. social) processes in terms of dynamic neural and social networks that govern exposure to alcohol-relevant cues, personal reactions to these cues, and the ability to regulate responses to them. Social factors cut across each of these dimensions: whether and how much drinking by members of a person’s social network can influence cue exposure, and the person’s reactivity to those cues may vary as a function of how susceptible they are to mimicking and adopting the behaviors of network members. In addition, the ability to change drinking behavior may in turn depend on the strategy the person adopts to regulate the desire to drink and their capacity to implement that strategy.